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Anti Mullerian Hormone (AMH) in Indian Patients Presenting With Infertility | Shivani Sachdev Gour



Introduction:
In the present scenario of advanced infertility treatment, there is lot of expectations and great disappointments when negative results are obtained. Hence good markers are needed to counsel patients about the probabilities of success and detect the poor prognostic patients so they can be counselled in greater detail. Most cases of success depend on the number and quality of ova produced. This in turn depends on the ovarian reserve. Ovarian reserve in the quantification of the number of follicle that are still present that can develop and release the ovum. As the age increases the reserve reduces. In age more than 40 the reserve is very poor. A number of tests are available to quantify the reserve. One of them is anti mullerian hormone. 

ANTI MULLERIAN HORMONE:           
Anti Mullerian Hormone (AMH) is considered as an important marker of the ovarian reserve.  It is secreted by the granulose cells (the cells surrounding the ovum) of the ovarian follicle. More the ova, more is the granulose cells and so the AMH is high. Very low values indicate exhaustion of the ova or low ovarian reserve. This is a poorer prognostic indicator for in-vitro fertilization (IVF) success, as a low AMH levels indicate that only few follicles will be formed and they may be of poor quality.  Conversely, high AMH levels are also clinically significant. High AMH levels may be seen in polycystic ovarian disease (PCOD) and it may be a predictor for ovarian hyper stimulation (OHSS) in IVF cycles. This means excess eggs are formed leading to water retention and rarely heart failure or even death during IVF cycles. Reliable data on AMH levels in Indian patients are limited. This study was done to compare the AMH levels in infertility patients presenting at our Infertility Centres in New Delhi. The AMH levels were correlated with age and western standard (normal) range available. Read full story here - http://articleneed.com/anti-mullerian-hormone-amh-in-indian-patients-presenting-with-infertility-dr-shivani-sachdev-gour/
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